ESPE Yearbook of Paediatric Endocrinology

...

Preface: In the last year the scientific community was again very active in research in both topics, differences/disorders of sex development (DSD) and transgender medicine.In DSD, next generation sequencing approaches revealed novel variants in genes so far not suspected to participate in sex development (e.g. MYRF, DHX37, PPP1R12A ). This expands the landscape of genes and proteins involved in DSD and provides further challenges for explaining...

Preface: Our PubMed search for DSD revealed close to 3000 articles and the search for transgender and gender dysphoria about 250 articles for the past 12 months. The topics in DSD were very broad ranging from new and old genes and their mechanism of action to diagnostic themes and new therapeutic options. Additional reports on gender dysphoria with DSD and articles on ethical discussions were published. In transgender, there were many articles on gender dysphoria and autism as...